From the summary: “Over the past 10 years, 278 new drugs have been approved by the Food and Drug Administration, according to data from the InnoThink Center for Research in Biomedical Innovation.  One hundred-and-seventy-five of them, or 63% of those approvals, came from 41 companies that had at least two new drugs approved during that time period.”  Here is the article with links to the underlying data.